medical-sciences

Toxicology & Dose-Response

The science of poisons and safe exposure — LD50 dose-response curves, bioaccumulation in food chains, exposure assessment modeling, threshold limit values, and quantitative risk characterization for chemical hazards.

toxicologydose-responseLD50bioaccumulationexposure assessmentthreshold limitrisk assessment

Toxicology is the study of how chemical, physical, and biological agents cause adverse effects in living organisms. Paracelsus observed that 'the dose makes the poison,' and modern toxicology quantifies this through dose-response relationships, exposure modeling, and risk assessment frameworks that protect public health.

These simulations let you fit LD50 curves, model bioaccumulation through trophic levels, assess multi-route chemical exposure, explore threshold limit values for workplace safety, and perform quantitative risk characterization — all with adjustable parameters and real-time visual feedback.

5 interactive simulations

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Bioaccumulation & Biomagnification

Simulate chemical bioaccumulation through trophic levels — explore how bioconcentration factor, trophic transfer efficiency, and elimination rate drive tissue concentration

simulator

Multi-Route Exposure Assessment

Simulate chemical exposure through multiple routes — explore how inhalation, ingestion, and dermal absorption contribute to total daily intake and hazard quotient

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LD50 Dose-Response Estimation

Simulate LD50 dose-response curves — explore how dose, slope factor, and organism sensitivity shape the sigmoidal mortality relationship

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Quantitative Risk Characterization

Simulate quantitative cancer and non-cancer risk assessment — explore how slope factor, exposure duration, and population size determine individual and population risk

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Threshold Limit Values & Workplace Safety

Simulate occupational exposure limits — explore how TLV-TWA, STEL, ceiling values, and exposure duration determine workplace safety compliance