life-sciences

Parasitology & Host-Parasite Dynamics

Model host-parasite interactions from molecular to population scale — including Plasmodium erythrocytic cycles, Anderson-May epidemiological models, helminth burden distributions, mosquito vectorial capacity, and the evolution of drug resistance in parasite populations.

parasitologymalariaPlasmodiumhelminthsvector capacitydrug resistancehost-parasiteAnderson-May

Parasitology studies organisms that live on or within a host at the host's expense. From the Plasmodium species causing malaria to soil-transmitted helminths infecting over a billion people, parasitic diseases remain among the greatest global health challenges. Understanding the quantitative dynamics of parasite transmission, burden distribution, and evolution is essential for designing effective control strategies.

These simulations let you explore the fundamental models of parasitology. Track Plasmodium through its erythrocytic cycle, apply the Anderson-May framework to model parasite transmission in populations, examine the characteristically overdispersed distribution of helminth burdens, calculate mosquito vectorial capacity, and observe how drug resistance emerges and spreads under selective pressure from antiparasitic treatment.

5 interactive simulations

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Parasite Drug Resistance Evolution Simulator

Model the evolutionary dynamics of drug resistance in parasite populations showing how treatment pressure, fitness costs, and mutation rates drive resistance spread

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Helminth Burden Distribution Simulator

Visualize the overdispersed distribution of worm burdens across a host population using the negative binomial model with adjustable aggregation

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Anderson-May Host-Parasite Model

Simulate the Anderson-May SIR framework with parasite load, showing how transmission rate, host recovery, and parasite-induced mortality shape endemic equilibria

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Plasmodium Erythrocytic Cycle Simulator

Model the intra-erythrocytic lifecycle of Plasmodium falciparum showing merozoite invasion, replication, and red blood cell lysis dynamics

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Mosquito Vectorial Capacity Simulator

Calculate vectorial capacity for mosquito-borne disease transmission incorporating biting rate, survival probability, vector competence, and extrinsic incubation period