Circadian biology studies the ~24-hour oscillations that govern nearly every physiological process in living organisms. From the molecular feedback loops of CLOCK and BMAL1 proteins to the behavioral rhythms of sleep and wakefulness, these internal timekeepers synchronize our biology with the solar day. Disruption of circadian rhythms is linked to metabolic disease, cancer, mood disorders, and impaired cognitive performance.
These simulations let you explore the transcription-translation feedback loops driving clock gene oscillations, map phase response curves to light pulses, model jet lag recovery across time zones, visualize how light intensity and timing entrain the master clock, and quantify the health impact of social jet lag — all built on peer-reviewed chronobiology models.